A well-trained scholar (researcher and teacher) as Clinical & amp; Cellular Immunologist focusing on innate and adaptive immunity, with major research interest in investigating the innate maturation of Dendritic Cells (DCs) followed by antigen cross-presentation via MHC-I to various T cell subsets. Further, curious to understand, how functional maturation of subtypes of DCs, influence the interaction with effector T cells, which determine the outcome of immune response in SELF (autoimmunity- T1D / MS) or NON-SELF (Cancers, Allografts, Infections-
Malaria, Schistosoma & Toxoplasma, TB, Listeria, Tetanus & Anthrax, RSV, SARS-CoV2, HIV & amp; Influenza) situations. As early-stage drug developer while working in the industry, I further extended my interest in the understanding of immune-dysregulation and immuno-pathogenesis of hereditary hemoglobinopathies (sickle cell / thalassemia) and hematological malignancies.
I have a mindset of a "Global Citizen and Servant Leadership", I cultivate and reinforce high performance teams with strong work ethics to utilize innovative work methods through social interaction and team spirit to achieve performance-based recognition and excellence. I strive to create a positive and productive work environment by fostering diversity and the inclusion of minorities. I strongly believe that interpersonal, cross-cultural and multidisciplinary approaches can achieve ambitious goals. I manage my teams with compassion, emotional intelligence, and
dynamic energy that inspires and empowers every person working around me. I am blessed with the intense passion to learn and to take on new challenges by applying strategic intelligence.
AREAS OF EXPERTISE:
Multidisciplinary experience in Fundamental & Clinical Immunology applicable to Cancer, Infectious Diseases, Autoimmunity and Inflammation, Tissue Transplantation and In SilicoOmics applications. Experience running Biomedical research programs & managing animal research, laboratory personnel and equipment. Proficient in immunological and molecular biology literature, techniques, and analysis. Subject matter specialist and highly experience in
research design process, research integrity, Bioethics and regulatory policies of IACUC (PHS/National Centre for the Replacement, Refinement and Reduction of animals in research -NC3Rs / ARRIVE), CDC, FDA, AAALAC. Experience in administrating vivarium and ABSL-3, biological and radiation safety as University Veterinarian. Highly trained in Cellular immunology experiments / functional characterization of cellular immunogenicity, immune-monitoring and data analysis / interpretation in mouse and primate model (specific pathogen free Baboon), and
humans (in vivo / ex vivo / in vitro functional characterization and data analysis). Histology & Imaging; Tissue culture & Cell line maintenance; Propagation and Biorepository. Molecular Cloning and Protein Expression & Purification. Human and Mouse T & B cells, Dendritic Cells, NKT cells Isolation, Purification and Functional Characterization. Many years of working experience in GLP settings in various labs.
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